Maternal Obesity Programs Offspring Development and Resveratrol Potentially Reprograms the Effects of Maternal Obesity
نویسندگان
چکیده
منابع مشابه
Maternal obesity at conception programs obesity in the offspring.
Risk of obesity in adult life is subject to programming during gestation. To examine whether in utero exposure to maternal obesity increases the risk of obesity in offspring, we developed an overfeeding-based model of maternal obesity in rats utilizing intragastric feeding of diets via total enteral nutrition. Feeding liquid diets to adult female rats at 220 kcal/kg(3/4) per day (15% excess cal...
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Background: Many factors affect exclusive breastfeeding, include method of delivery, parity, maternal age and education, smoking, ethnicity, pregnancy complications, infant health, and environmental factors such as hospital practices, and social support. Recently, maternal obesity has been suggested as a risk factor for poor breast-feeding practices whose role has not...
متن کاملMaternal Obesity, Metabolic Health, and Prenatal Programming of Offspring Obesity
Children born to overweight and obese women, as compared to those of normal weight women, have greater risk for becoming obese themselves and suffering comorbid metabolic health problems. Evidence is accumulating that this increased susceptibility is at least partially attributed to a prenatal programming effect, whereby obesogenic factors in the intrauterine environment alter fetal development...
متن کاملMechanisms by which maternal obesity programs offspring for obesity: evidence from animal studies.
Maternal obesity can profoundly affect offspring phenotype and predisposition to obesity and metabolic disease. Carefully controlled studies in precocial and altricial mammalian species provide insights into the involved mechanisms. These include programming of hypothalamic appetite-regulating centers to increase orexigenic relative to anorexigenic drive; increasing maternal, fetal, and offspri...
متن کاملMaternal obesity and risk of Down syndrome in the offspring.
OBJECTIVE The objective of this article is to determine if maternal obesity is associated with an increased risk of Down syndrome in the offspring and whether the risk estimates for trisomy 21 based on combined screening is affected by maternal body mass index (BMI). METHODS Study group I consisted of a nationwide cohort of 1 568 604 women giving birth; outcome was infants born with Down synd...
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ژورنال
عنوان ژورنال: International Journal of Environmental Research and Public Health
سال: 2020
ISSN: 1660-4601
DOI: 10.3390/ijerph17051610